The SH3BP2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SH3 domain binding protein 2, and SH3BP2. This antibody recognizes Human, Mouse, and Rat antigen. The SH3BP2 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene